Imetelstat: Late-Stage Study Successful For Blood Cancer Drug

On Wednesday, Geron disclosed that its experimental blood cancer medication helped more patients avoid blood transfusions than a placebo in a late-stage trial, sending its shares up 50%.

Compared to a placebo in a late-stage trial, Geron’s investigational blood cancer therapy helped more patients attain independence from blood transfusions, the company announced on Wednesday, driving its shares up 50%.

The company tested her medicine on patients with a particular form of myelodysplastic syndromes .To stop the anemia, patients with the condition need blood transfusions.

2023, in the United States and Europe’s second half of that year, the business intends to submit applications for approval. The medicine is anticipated to go on sale in 2024.the pharmaceutical business, nearly 40% of the patients taking medicine demonstrated transfusion independence for eight weeks, as opposed to 15% of the 60 patients taking a placebo.

The findings imply that using the medication “may be affecting the course of the disease,” according to Chief Medical Officer Faye Feller. This medicine also accomplished its secondary objective.Low no of platelet and white blood cell counts were among the most prevalent adverse effects in the late stage. The business said that these negative impacts weren’t unusual.

Geron also tests these medicine for the uncommon bone marrow malignancy known as myelofibrosis, and an interim analysis is anticipated in 2024.

Written by Aly Bukshi

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